Akihito Iida, M. Yamashita,
Jul 1, 1988
Citations
0
Influential Citations
13
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
Chiral diphenylphosphine and diphenylphosphinite derivatives of carbohydrates such as D-glucose, D-galactose, and L-rhamnose were used as the ligand of metal catalysts for asymmetric Grignard cross-coupling reaction. Coupling of s-butylmagnesium bromide with bromobenzene was carried out in the presence of nickel or palladium chloride with the chiral ligand. The highest optical yield was observed when D-galactose ligand was used.