B. Baskar, G. Pandian, K. Priya
Dec 13, 2004
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Influential Citations
43
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Journal
Tetrahedron-asymmetry
Abstract
Abstract Enantioselective bioreduction of alkyl 2-oxo-4-arylbutanoates and 2-oxo-4-arylbut-3-enoates mediated by Candida parapsilosis ATCC 7330 resulted in the formation of the corresponding ( S )-2-hydroxy compounds in high enantiomeric excesses (93–99%) and good isolated yields (58–71%). The absolute configuration of enantiomerically pure ethyl 2-hydroxy-4-( p -methylphenyl)but-3-enoate obtained by the reduction of the corresponding keto ester was assigned by 1 H NMR using Mosher’s method.