T. Arai, A. Tsuchida, T. Miyazaki
Jan 30, 2017
Citations
0
Influential Citations
15
Citations
Journal
Organic letters
Abstract
A chiral bis(imidazolidine)pyridine (PyBidine)-Ni(OTf)2 complex smoothly catalyzed an asymmetric Friedel-Crafts reaction of 2-vinylindoles with nitroalkenes to give chiral indoles in a highly enantioselective manner while maintaining the 2-vinyl functionality. The chiral 2-vinylindoles offer unique chiral scaffolds for diverse transformations.