K. Harada, I. Nakamura
Oct 5, 1978
Citations
0
Influential Citations
4
Citations
Journal
Chemistry Letters
Abstract
Optically active dimethyl aziridine-2,3-dicarboxylate(VI) was asymmetrically synthesized from dimethyl meso- and racemic dibromosuccinate(I and II), dimethyl bromofumarate(III) and dimethyl bromomaleate(IV) by treating with optically active α-methylbenzylamine. The optically active aziridine(VI) was hydrogenolyzed and hydrolyzed to form optically active aspartic acid(VII). The optical purity of VHI reached up to 37%.