S. Kim, T. Jeon, I. S. Min
Jul 11, 2012
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0
Influential Citations
23
Citations
Journal
Tetrahedron Letters
Abstract
A concise asymmetric total synthesis of (S)-dapoxetine from commercially available 3-chloropropiophenone is described. The key step includes a highly stereoselective amination of chiral benzylic ether, with the retention of stereochemistry, using chlorosulfonyl isocyanate.