M. LangeJosephusH, H. J. Sanders, J. V. Rheenen
Mar 23, 2011
Citations
0
Influential Citations
2
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A novel synthetic route to the highly selective and orally active cannabinoid CB 1 receptor inverse agonist ibipinabant is described which combines the use of inexpensive, commercially available reagents and mild reaction conditions with a high degree of atom-efficiency. The method is expected to enable the rapid synthesis of a variety of sulfonylguanidines.