Teng-yueh Chen, Tetutaro Sanjiki, H. Kato
Oct 1, 1967
Citations
0
Influential Citations
7
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
The tosylation of 1-t-butyl-3-azetidinol in pyridine gave 1-t-butylazetidinyl-3 tosylate, but 1-cyclohexyl-3-azetidinol gave mainly N-tosyl-1-cyclohexylamino-3-chloro-2-propanol. The reaction of both the azetidinols with p-nitrobenzoyl chloride in pyridine gave the 3-nitrobenzoates, while in acetone 1-cyclohexyl-3-azetidinol gave a ring cleavage product. The preparation of 1-t-butylazetidine-3-carboxylic acid is described.