B. Reddy, Supriya Ghanty, Ch. Kishore
Jul 30, 2014
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
The coupling of aldehydes or ketones with (2-(4-methoxyphenyl)-4-methylenetetrahydrofuran-3-yl)methanol in the presence of nitriles under the influence of 5 mol % tris(pentaflourophenyl)borane at room temperature afforded a novel series of cis -fused hexahydro-1 H -furo[3,4- c ]pyran derivatives in good yields with high selectivity. This is the first report on the synthesis of hexahydro-1 H -furo[3,4- c ]pyranyl amide through a sequential Prins/Ritter reactions using B(C 6 F 5 ) 3 as a mild Lewis acid.