Haruyo Sato, Shinzo Imamura, Yukishige Kitano
1984
Citations
0
Influential Citations
1
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
2-(4-Cyanobutyl)-4,5,6,7-tetrahydrobenzimidazole was obtained by treating 2-aminocyclohexanone oxime with ethyl acetimidate hydrochloride in acetic acid at below 50 °C, though only 2-methyl-4,5,6,7-tetrahydrobenzimidazole was produced by the reaction of 2-aminocyclohexanone oxime and free ethyl acetimidate in neutral solvents. A novel Beckmann fission reaction of dimeric 2-aminocyclohexanone oxime is presumed to participate in the formation of 2-(4-cyanobutyl)-4,5,6,7-tetrahydrobenzimidazole.