S. Funakoshi, E. Murayama, Lili Guo
1988
Citations
0
Influential Citations
15
Citations
Journal
Journal of The Chemical Society, Chemical Communications
Abstract
An easily preparable dimethoxybenzhydrylamine derivative, 3-(α-Fmoc-amino-4-methoxybenzyl)-4-methoxyphenyl propionic acid (Fmoc = fluoren-9-ylmethoxycarbonyl) is a useful precursor of the C-terminal amide, when applied to Fmoc-based solid phase peptide synthesis; as a cleavage reagent from the resin, thioanisole-mediated trimethylsilyl bromide in trifluoroacetic acid is recommended.