A. Khalil
Nov 1, 2006
Citations
1
Influential Citations
28
Citations
Quality indicators
Journal
Archives of Pharmacal Research
Abstract
A phytochemical investigation of stems fromSalvadora persica resulted in the first isolation of four benzylamides from a natural source. The isolated compounds were identified as butanediamide,N1,N4-bis(phenylmethyl)-2(S)-hydroxy-butanediamide (1),N-benzyl-2-phenylacetamide (2),N-benzylbenzamide (3) and benzlurea (4). The structure elucidation was accomplished using spectroscopic methods, especially 2D NMR and HREIMS. Compound2 revealed a significant inhibitory effect on human collagen-induced platelet aggregation, and a moderate antibacterial activity againstEscherichia coli.