H. Ohtaka, M. Hori, R. Iemura
Nov 1, 1989
Citations
0
Influential Citations
4
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
The metabolites of 1-[bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride (KB-2796, 1), a cerebral vasodilator, and related compounds were synthesized to confirm the proposed structures. The structures of the metabolites (3-5) in rats were identified by means of synthesis of the authentic compounds.