Rita Elek, L. Kiss, J. Praly
May 23, 2005
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0
Influential Citations
14
Citations
Journal
Carbohydrate research
Abstract
By reaction with arylhydroximoyl chlorides, 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-galactopyranose was converted to the corresponding beta-D-galactopyranosyl-thiohydroximates, which gave predominantly (1S)-D-galactopyranosylidene-spiro-oxathiazoles on illumination in the presence of NBS. Conventional O-deacetylation of both thiohydroximates and oxathiazoles gave weak inhibitors of E. colid-galactosidase (Ki 1.1-11.1 mM).