Y. B. Lee, Y. Goo, Jae Keun Lee
Dec 1, 1988
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Journal
Archives of Pharmacal Research
Abstract
Abstract2-Mercaptoethanol, thioglycolic acid, glutathione, 3-mercapto-1,2-propanediol and 3-mercapto-2-butanol showed catalytic activities on the hydrolysis of α-aminophenylacetonitrile to phenylglycineamide at the rate of 12.19×10−2, 8.03×10−2, 6.83×10−2, 8.60×10−2 and 6.04×10−2 mM min−1, respectively. The hydrolysis rate was faster in buffer than in water. The hydrolysis of the nitrile compound to phenylglycine was limited.