Tom A. Beardslee, S. Picataggio
Oct 1, 2012
Citations
1
Influential Citations
73
Citations
Quality indicators
Journal
Lipid Technology
Abstract
Adipic acid (hexanedioic acid, C6H10O4) is a high-volume dicarboxylic acid used as a chemical intermediate in the commercial manufacture of nylon 6,6, thermoplastic polyurethane resins, plasticizers, adhesives and synthetic lubricants, with an estimated global market worth approximately $6.3 billion. We report here the development of a robust industrial yeast strain and fermentation process for production of bio-based adipic acid at high yield and selectivity from any vegetable oil, regardless of its fatty acid composition. Bio-based adipic acid could alleviate many of the drawbacks associated with adipic acid produced from petrochemical sources and offer a sustainable alternative to benzene price swings as well as a significant reduction in greenhouse gas emissions.