M. P. Sobolevskaya, V. Denisenko, S. Fotso
Mar 1, 2008
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Journal
Russian Chemical Bulletin
Abstract
A new cyclic dipeptide, 3-a[(4-hydroxybenzyl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione (1) together with the known compounds, 2,3-dihydroxybenzoic acid (2), and 6-(3-methylbut-2-enyl)isatin (3) were isolated from the actinobacterium Streptomyces sp. GW 33/1593. Compounds 1 and 2 possessed cytotoxic activity against the sea urchin Strongylocentrotus intermedius embryos.