M. Delaforge, P. Janiaud, P. Levi
Oct 1, 1980
Citations
1
Influential Citations
40
Citations
Quality indicators
Journal
Xenobiotica; the fate of foreign compounds in biological systems
Abstract
1. The epoxidation of allylbenzene, safrole, estragole, eugenol and eugenol methyl ether was investigated in rats pretreated with these compounds and also in vitro using hepatic microsomal preparations and adult rat liver cell cultures. 2. Dihydrodiols were detected in the urine and liver of rats pretreated with allylbenzene compounds. Similarly, incubation of allylbenzene epoxides with hepatic microsomal preparations and adult rat liver cell cultures gave rise to the formation of dihydrodiols.