Yu-Peng He, Hao Tan, Lars Arve
Jun 6, 2011
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0
Influential Citations
11
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Journal
Chemistry, an Asian journal
Abstract
A full account on the synthesis of the antibiotic natural product biphenomycin B and several derivatives is reported, which employs a Suzuki coupling reaction of a free carboxylic acid and macrolactam formation as key transformations. Liberal exchange of the central amino acid was demonstrated. This procedure gave derivatives to study the influence of the polar side chain of the central amino acids on translation inhibition.