R. Ghosh, S. Maiti, Soumen Ghosh
2007
Citations
0
Influential Citations
10
Citations
Journal
Synthesis
Abstract
Bismuth(III) chloride generated in situ from the procatalyst bismuth(III) oxychloride and acetyl chloride efficiently catalyzes the one-pot synthesis of β'-acetamido-β-dicarbonyl compounds from aldehydes, enolizable β-diketones, or β-oxo esters and acetyl chloride in acetonitrile solution and under solvent-free conditions at room temperature; in the case of the β-oxo ester derived products, these are obtained with moderate to excellent diastereoselectivity in favor of the pref-isomer. X-ray crystallographic analysis of one pref-β'-acetamido-β-oxo ester exhibits C-H···O and N-H···O intermolecular interactions in the three-dimensional supramolecular assembly.