R. Klimek, E. Małolepszy
Dec 1, 1968
Citations
0
Influential Citations
1
Citations
Quality indicators
Journal
Clinica chimica acta; international journal of clinical chemistry
Abstract
Abstract In 62 women with goiter the cystine aminopeptidase (oxytocinase) activity was assayed by chemical method, using l -cystine-di-β-naphthylamide as substrate. Levels of enzyme show statistically significant differences between women with simple, nontoxic (16 cases) and toxic goiter (46 cases). In the former these values are within limits observed in healthy persons, and in the latter they exceed the upper limit of normal by 70%. Assay of oxytocinase may prove useful in studies on the hormonal disorders connected with the hypothalamus.