Yi‐feng Zhou, Rui Wang, Zhaoqing Xu
Feb 23, 2004
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Influential Citations
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Tetrahedron-asymmetry
Abstract
Abstract The N-terminal protected amino acid (Boc- l -proline) is a chiral ligand for the enantioselective phenylacetylene addition to aromatic aldehydes, thus expanding the utility of the simplest enzyme, proline, in asymmetric catalysis. Good yields and enantioselectivities (up to 77% ee) were achieved.