Patricia Bondia, C. Flors, J. Torra
Aug 9, 2021
Citations
0
Influential Citations
5
Citations
Journal
Chemical communications
Abstract
We report that Thioflavin T (ThT), the reference fluorogenic probe for amyloid detection, displays photodynamic activity against bacterial biofilms. ThT recognizes key structures of the biofilm matrix, disrupting the complex architecture and efficiently inactivating bacterial cells. We also show that ThT phototherapy synergistically boosts the activity of conventional antimicrobials.