Jian Cui, Qun Jia, Ruozhu Feng
Feb 26, 2014
Citations
0
Influential Citations
57
Citations
Journal
Organic letters
Abstract
A widely used Lewis acid BF3·Et2O was shown to be capable of acting as an efficient fluorinating agent in an intramolecular aminofluorination reaction of homoallylic amines to provide 3-fluoropyrrolidines mediated by a commercially available hypervalent iodine(III) reagent PhIO at room temperature. A mechanism involving a carbocation intermediate was proposed on the basis of several experimental evidence.