Amrita Das, Kenji Watanabe, H. Morimoto
Oct 18, 2017
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0
Influential Citations
13
Citations
Journal
Organic letters
Abstract
Boronic acid was used to accelerate a three-component reaction of indoles, thiols, and glyoxylic acids for the synthesis of α-sulfanyl-substituted indole-3-acetic acids. Boronic acid catalysis to activate the α-hydroxy group in α-hydroxycarboxylic acid intermediates and intramolecular assistance by free carboxylic acid were the keys to accelerating the product formation.