C. Lugar, D. Magee, M. D. Adrian
Dec 15, 2003
Citations
0
Influential Citations
9
Citations
Quality indicators
Journal
Bioorganic & medicinal chemistry letters
Abstract
The pharmacology and SAR of representative equine estogens is described. 17alpha-Dihydroequilenin was found to prevent bone loss after 5 weeks of oral administration to ovariectomized rats. The stereochemical significance of the D-ring and the C/D ring juncture was investigated with a series of benzothiophene-based equilenin analogues.