Mateus Mittersteiner, N. Zanatta, H. Bonacorso
Apr 14, 2020
Citations
0
Influential Citations
10
Citations
Journal
Synthesis
Abstract
Abstract 5-Bromo- and 5,5-dibromo-1,1,1-trihalo-4-methoxypent-3-en-2-ones (brominated enones) have proven to be attractive building blocks for the construction of heterocyclic and polyheterocyclic compounds bearing a trihalomethyl moiety through interesting cyclocondensation, alkylation, and cycloaddition reactions. This review compiles all of the reactions conducted with these brominated enones since they were first disclosed in 2001. 1 Introduction 2 Synthesis and Initial Applications 3 Synthesis Using First-Generation Intermediates 4 Synthesis Using Second-Generation Intermediates 5 Synthesis Using Third-Generation Intermediates 6 Conclusions