P. R. K. Mitchell, İbrahim F. Sengul, Hakan Kandemir
Sep 30, 2012
Citations
0
Influential Citations
15
Citations
Journal
Tetrahedron
Abstract
Abstract The bromination of activated 4,6-dimethoxyindoles can be carried out effectively provided that an electron-withdrawing group is also present. Thus the range of products includes 2-bromo-7-formyl or 2-bromo-7-acetylindoles 13a – c and 16 , 7-bromo-2-acetylindole 21 , 2,5-dibromo-7-acetylindole 17 , 2,5-dibromo- N -sulfonylindole 27 , and 2,7-dibromo- N -acetylindole 24 . Acetyl and sulfonyl protecting groups on nitrogen can be removed to give 2-bromoindoles 28a – b , 2,5-dibromoindole 29 , and 2,7-dibromoindole 4 .