T. Kano, F. Shirozu, K. Maruoka
Oct 5, 2010
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0
Influential Citations
23
Citations
Journal
Chemical communications
Abstract
One-pot stereoselective synthesis of bromohydrins as a useful chiral building block was achieved by the reaction of Grignard reagents with optically active α-bromoaldehydes, which were in situ generated by direct asymmetric bromination of aldehydes catalyzed by a binaphthyl-based secondary amine (S)-3.