Xu Yingzhou, D. Hu, Zheng Hui
Sep 27, 2019
Citations
0
Influential Citations
4
Citations
Journal
Tetrahedron
Abstract
Abstract This article first time describes triphosgene (BTC) as an oxidant while the non-toxic and easy-to-handle potassium bromide (KBr) as the source of bromine to the bromination reaction of aromatic substrates. The novel brominating protocol gives excellent para-regioselectivity of the alkoxyl/hydroxyl arenes and high yield, offering good potential of commercial scale applications. The mechanism of “Triphosgene oxidize bromide” was proposed.