Jing Li, Zequan Li, Xun Zhang
May 31, 2017
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Influential Citations
8
Citations
Journal
Organic chemistry frontiers
Abstract
A highly enantioselective bromohydroxylation of aryl olefins with flexible functionalities has been achieved with (DHQD)2PHAL as a catalyst and H2O as a nucleophile, giving a variety of optically active bromohydrins with up to 98% ee. An acid additive has been found to be beneficial for the reactivity and enantioselectivity.