F. Gillin, S. David, Reiner
Aug 1, 1982
Citations
1
Influential Citations
119
Citations
Quality indicators
Journal
Antimicrobial Agents and Chemotherapy
Abstract
Bruceantin, purified from an Ethiopian plant used to treat dysentery, killed Entamoeba histolytica in vitro (IC50 [the concentration of drug which decreased the number of colonies to half that of controls] = 0.018 microgram/ml). Six related quassinoids of 17 tested were also amoebicidal. No relationship between quassinoid structure and amoebicidal activity was apparent.