I. Celino, A. A. D. Medeiros, Gernot Zeissler
2007
Citations
0
Influential Citations
29
Citations
Journal
Synthetic Metals
Abstract
In an elegant stepwise process for the production of intermediates of thromboxanes such as TXB2 from a chiral glucose starting material such as alpha -methylglucoside, those steps comprising: (1) (2) (3) (4) (5) A key modification introduced in this synthetic sequence is the use of 4-dimethylaminopyridine for the selective alkylation of primary alcohols in the presence of unprotected secondary alcohols and for the controlled acylation of methylglucoside. The former application has large potential use in the synthesis of nucleosides, polynucleotides, and carbohydrate derivatives.