Q. Fu, Yangyuan Han, Yi-fei Xie
Sep 1, 2018
Citations
0
Influential Citations
21
Citations
Journal
Journal of Molecular Structure
Abstract
Abstract A series of carbamazepine cocrystals with aromatic carboxylic acids have been prepared, including (CBZ)1(DBA)1, (CBZ)2(DBA)1(CH3OH)1 (DBA = 2,3-dihydroxy benzoic acid), (CBZ)1(NA)1(H2O)1 (NA = 1-naphthoic acid) and (CBZ)1(AC)1 (AC = anthracene-9-carboxylic acid). The synthons formed in CBZ cocrystals, e.g. amide···acid heterodimer, amide···amide homodimer, and amide···acid···H2O heterosynthon have been discussed and compared with synthons in reported CBZ cocrystals in CSD. The solid state properties of these cocrystals, such as transformation, solubility and their stabilities have been discussed in the article.