V. S. Rajan, J. Sng
Mar 1, 1974
Citations
0
Influential Citations
1
Citations
Journal
Singapore medical journal
Abstract
Carbenicillin a semi synthetic, bactericidal antibiotic, is effective against a variety of gram negative organisms. Lts unique activity against pseudomonas aeruginosá and Proteus species is well recognized; but its wide range of activity in urinary tract infections has lent its use in these infections. The original salt; disodium carboxybenzyl penicillin was administered paranterally because of poor intestinal absorption and acid lability. Recently the indanyl ester of carbenicillin was shown to be acid stable and easily absorbed by the gastro-intestinal tract. The oral formulation now possible, has facilitated the use of the antibiotic to ambulatory patients with infections such as gonococcal urethritis.