Umesh K. Mishra, N. Ramesh
May 30, 2020
Citations
0
Influential Citations
2
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Synthesis of trans-4-hydroxy- d -proline and the corresponding prolinol has been accomplished starting from 4,6-di-O-benzyl-3-deoxy- d -glucal, an enol-ether derived from d -glucose, through oxidative cleavage of a vicinal diol intermediate as the key step. This work represents a practical approach to an unnatural, yet synthetically and biologically very significant, amino acid.