Hongjian Song, Yongxian Liu, Qingmin Wang
Jun 19, 2013
Citations
0
Influential Citations
48
Citations
Journal
Organic letters
Abstract
4-Iodomethyl substituted tetrahydro-β-carbolines, the core structure of numerous natural products and bioactive molecules, are readily prepared via I2-promoted cascade electrophilic cyclization. The reactivity differences of olefins and alkynes ensure that the reaction proceeds smoothly. This methodology was successfully applied to the formal synthesis of oxopropaline G.