C. Xie, Zhenya Dai, Yadi Niu
Feb 5, 2018
Citations
0
Influential Citations
18
Citations
Journal
The Journal of organic chemistry
Abstract
A cross-coupling strategy of palladium-catalyzed ortho-C-H bond activation and intramolecular addition of N-C annulation to synthesize isoquinolin-1(2H)-ones has been developed. A wide range of α-bromo ketones with different substituents proceeded smoothly in this reaction, and varieties of isoquinolin-1(2H)-one derivatives were obtained in moderate to good yields.