Su Chen, Pengbo Zhang, Wanyun Shu
Oct 25, 2016
Citations
0
Influential Citations
46
Citations
Journal
Organic letters
Abstract
Pyrrolo[1,2-a]indole is a common structural motif found in many natural products and pharmaceuticals. A silver-mediated oxidative phosphinoylation of N-propargyl-substituted indoles was used to construct a variety of 2-phosphinoyl-9H-pyrrolo[1,2-a]indoles under mild conditions. This transformation offers a straightforward route to the formation of the C-P bond, cyclization, and isomerization in one step.