Zijuan Wang, Wenteng Chen, Haofan Luo
Feb 25, 2020
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Influential Citations
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Journal
Synthesis
Abstract
Abstract An efficient and simple synthesis of substituted 1H-pyrrole-3-carbonitriles was developed. This reaction is a palladium(II)-catalyzed cascade of C(sp)–C(sp2) coupling followed by intramolecular C–N bond formation. The method can tolerate various substrates with satisfactory yields. Its ligand-free conditions and high efficiency make this method particularly attractive.