J. T. F. and, A. Lavoie
Nov 2, 2001
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Influential Citations
135
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Quality indicators
Journal
Organometallics
Abstract
The combination of l-prolinamide with (p-CymeneRuCl2)2 or (Cp*RhCl2)2, in the presence of KOH/2-propanol, has been found to generate catalysts in situ that are capable of enantioselectively reducing aryl ketones to the respective (R)-alcohols. Furthermore, when the catalyst derived from (p-CymeneRuCl2)2/l-prolinamide was applied to the asymmetric reduction of 1‘-tetralone at −24 °C, (R)-tetralol was produced in 93% ee.