A. Solankee, S. Lad, Sejal Solankee
Oct 1, 2009
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0
Influential Citations
21
Citations
Journal
ChemInform
Abstract
2, 4-Bis-ethylamino-6-[ 4' - 3 "-(substitutedphenyl/2"'-furanyl)-2'-propenone-1"-yl,} phenyl amino]-s-triazine 5a-d have been prepared by treating ketone 4 with different substituted aromatic and heterocyclic aldehydes in the presence of alkali. These chalcones 5a-d on cyclisation with hydrazine hydrate and guanidine nitrate to form pyrazolines 6a-d and aminopyrimidines 7a-d respectively. The structures of the synthesized compounds have been established on the bases of IR, 1 H NMR and elemental analysis. The compounds have been evaluated for antibacterial activity against E. coli, S. paratyphi-A, S. aureus and B. subtilis.