Vanessa E DeLey Cox, M. Racine, Erin Pueblo
Apr 1, 2020
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Journal
The FASEB Journal
Abstract
Fluoroacetate, a severely toxic metabolic poison, has historically been used to control rodent and predator populations. Due to safety concerns, its use is highly restricted in the United States; however, other countries have fewer regulations. Although the mechanism of action is known, no countermeasures have been identified, and accidental or intentional ingestion by humans is often fatal. Case studies documenting exposures describe a variety of nonspecific signs and symptoms, including cardiac dysfunction, pulmonary edema, and neurological symptoms.