K. Kimura, A. Watanabe, M. Machida
May 21, 1971
Citations
0
Influential Citations
7
Citations
Journal
Biochemical and biophysical research communications
Abstract
Abstract The activity of E. coli ribosomes to synthesize polyphenylalanine under the direction of polyuridylic acid is inhibited by certain maleimide derivatives. Using a fluorescence-labeled sulfhydryl reagent, N-( p -(2-benzimidazolyl)phenyl)maleimide, it is confirmed that the inhibition takes place through covalent bond formation of this reagent with cysteine-sulfhydryl groups of the ribosomal proteins.