S. Hu
1986
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Journal
West China Journal of Pharmaceutical Sciences
Abstract
In the studies of synthesis of domiphen bromide, the chemical kinetic method was used. It shows that the reaction of n-dodecyl bromide and N- (2-phen-oxyethyl)-N, N-dimethylamine in acetone accords with second order reaction. The r-ate constant (K)is 1.56×10~(-4)+0.14×10~(-4)/ mol. sec. Thereby the technological conditions are c-hosen. Good results have obtained on industrial production.