A. Upton, D. Doherty, G. S. Melville
May 1, 1959
Citations
0
Influential Citations
2
Citations
Journal
Acta Radiologica
Abstract
A major goal of the radiobiologist is the control of radiosensitivity. Encouraging progress toward this end has been made with the synthesis of mercaptoethylguanidine (MEG), a compound which enables mice to survive otherwise lethal roentgen doses (14). To ascertain whether this chemical protects against induction of leukemia by irradiation, mice were pretreated with the drug, then given graded sublethal doses of roentgen rays. The incidence of leukemia in these animals was compared with that in similarly irradiated mice treated with saline placebos.