T. Wakamiya, T. Teshima, I. Kubota
Sep 1, 1974
Citations
1
Influential Citations
13
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
γ-Hydroxy-β-lysine is a new basic amino acid isolated from the hydrolyzates of antitubercular peptides, tuberactinomycin A and N. In order to confirm the structure and establish the stereochemistry of the amino acid, two diastereoisomers of γ-hydroxy-DL-β-lysine were synthesized by Arndt-Eistert synthesis via β-hiydroxyornithine. Synthetic erythro and threo isomers were found to be identical spectroscopically and chromatographically with the corresponding forms obtained from the antibiotics respectively.