O. Nurkenov, S. Fazylov, Z. Satpaeva
Apr 19, 2013
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Journal
Russian Journal of General Chemistry
Abstract
The reaction of N-morpholinylacetic acid hydrazide with various isothiocyanates and potassium thiocyanate resulted in the corresponding potentially biologically active thiosemicarbazide derivatives. Potassium N′-(2-morpholin-4-ylacetyl)hydrazinocarbothioate was synthesized and involved into heterocyclization in acidic environment to yield cyclic 5-(morpholinomethyl)-1,3,4-thiadiazole-2-thione. The structure of the synthesized compounds was established by IR, 1H NMR spectroscopy, mass spectrometry, and XRD analysis.