Wu Dong-Bing, Yang Xiao-feng
2005
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Journal
Journal of Northwest University
Abstract
Aim To describe a novel flow injection chemiluminescence (CL) method for the determination of dihydralazine sulfate (DHZS). Methods The method is based on the oxidation of DHZS by acidic permanganate solution to give weak CL signal, which is dramatically enhanced by rhodamine B. The CL signal is linear with DHZS concentration in a certain range. Results The CL emission allows quantitation of DHZS concentration in the range 5.0~800 ng/mL with a detection limit of 1.9 ng/mL (3σ). Conclusion The method has been applied to the determination of DHZS in pharmaceutical preparations.