M. Roks, R. Nolte
Sep 1, 1992
Citations
0
Influential Citations
59
Citations
Journal
Macromolecules
Abstract
A synthetic model of a natural channel-forming ionophore is described. It is based on a polymer with a rigid backbone, viz. a polymer of an isocyanide, [R-N=C<] n . Each of the polymer side chains R contains a crown ether ring. Due to the rigid 4/1 helical structure of the polymer the cross ether rings are cofacially stacked and form four channels which run parallel to the polymer helix axis. The channels are better ion-complexing agents than low molecular weight cross ethers. Evidence is presented that the channel structures can be incorporated in the bilayers of dihexadecyl phosphate vesicles