Xuechen Li, S. Danishefsky
Mar 28, 2008
Citations
1
Influential Citations
112
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Journal
Journal of the American Chemical Society
Abstract
Thermolysis of isonitriles with carboxylic acids provides, in one step, N-formyl imides (see, for example, 8 + 19 --> 21). The resultant N-formyl group can be converted to N-H, NCH2OH, or NCH3. This chemistry allows for a new route for synthesizing beta-N (asparagine)-linked glycosyl amino acids.